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Antibiotics during pregnancy

Equine-Reproduction.com Bulletin Board » Breeding Problem Mares - Volume 2 » Antibiotics during pregnancy « Previous Next »


Author Message
 

marina novotna
Weanling
Username: Marina

Post Number: 27
Registered: 06-2008
Posted on Wednesday, August 04, 2010 - 06:12 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

I have a mare, I bought her last year and she had very bad cervix - in fact almost no cervix during the heat and 1 finger open during diestrus. I discussed her here and got some great advices.

She was caslicked, then again a bit more, put on more weight and put on Regumate on day 4 post breeding several times. She is 23 years old and had some other problems as well, but... she is finaly in foal, 35 days today.
I have no idea, how closed the cervix is right now. And we dont want to touch it. Sooo - I would like to ask you, would you consider her high risk regarding placentitis or not?
I read somewhere on this site, that antibiotics are used - 5 days every month if I remember correctly? Would you use it in this case or not? If yes, what antibiotics do you use and what is the correct protocol?

Thank you very much,
Marina
 

Kristen B.
Neonate
Username: Kristen_b

Post Number: 7
Registered: 06-2010
Posted on Wednesday, August 04, 2010 - 11:42 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

I believe the protocol is 7-10 days a month of smz beginning at 4 months. Have been wondering about doing with a mare of mine as well!
 

Jos
Board Administrator
Username: Admin

Post Number: 2974
Registered: 10-1999
Posted on Thursday, August 05, 2010 - 12:36 am:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

If the cervix is compromised as you describe, then yes, she is high risk.

SMZ's for 5-7 days each month from the fourth month of pregnancy onward may help; you might also want to put her on supplemental progestins, as that will assist in keeping the cervix more tightly closed - daily Regumate, or biorelease altrenogest or P4 progesterone from BET Pharm - the latter being easier to deal with.
 

marina novotna
Weanling
Username: Marina

Post Number: 28
Registered: 06-2008
Posted on Thursday, August 05, 2010 - 06:10 am:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

Many thanks for your answers.

She is currently on daily Regumate, we started her on day 4 post breeding.

We (with my vet) have to figure out yet, how to order from BET Pharm, because we are located in Europe. We wanted to order estradiol from them to try the protocol described here: http://wvc.omnibooksonline.com/data/papers/2009_V426.pdf under Hyper-Responders. We used Zylexis and dexamethasone in adition to flushing 4-8 hours post breeding and oxytocin protocol for the last two mares and I believe it helped us to get them in foal (including this one with compromised cervix).
I have 7 mares age 19-23 with different repro problems, 6 of them now in foal (and for sure they would not be in foal if I didnt find this site, so thank you very much again). The last one doesnt ovulate, has very small ovaries without follicles (age 22). She responds to the protocol described here: http://www.betlabs.com/anomare.htm - the last one - only once upon a time. Only one ovulation this year, protocol used three times. Right now we are trying it for the fourth time. If you have another idea, what to try with her, I would appreciate the advice very much. We ruled out cushing and lack of total T4.



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