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Problem with short heat cycles

Equine-Reproduction.com Bulletin Board » Breeding Problem Mares - Volume 2 » Problem with short heat cycles « Previous Next »


Author Message
 

Barbara Lewis
Yearling
Username: Baraka

Post Number: 65
Registered: 06-2008
Posted on Wednesday, June 30, 2010 - 10:32 am:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

I have a 9 yr old mare who is driving me nuts this year. I need advice.

1st time bred, she went to a large farm who ultrasounds every other day (to determine heat, etc.) and never got in foal after three heat cycles. No reason found.

Second time, 2 years ago, everything went well. She showed strong heat, 6 day heat cycles, and stood well for the stallion. She got in foal on the 2nd heat cycle, and producing a beautiful, healthy filly. This year no one can figure out what she is doing.

This year she returned to the same farm for live cover and was put in with one 2 yr. old so as not to be intimidated by aggressive mares. They tease daily. When in heat, she runs to the tease stallion,

First cycle she was bred with one cover, and was out. Later ultrasound showed that she was not in foal, but had a 46 follicle. That evening, an attempt was made to cover her, and she panicked, trying to get away from the stallion. She was not covered, thinking maybe a pregnancy was missed.

Later she had another ultrasound, was not pregnant so had a thorough breeding fitness exam. She had some multiple follicles, and one seemed to be developing. Tone was good, ovaries good, uterus a little small (as has always been the case), and was found to be in good reproductive condition.

She did not come back in heat for 54 days (still teased daily), so was bred the first day she showed heat, and on day 3 she was out of heat.

Next she comes home. I had an opportunity to breed with shipped semen to a stallion that was about to leave the country, so gambled on her.

Lutylase was used. She came in, showed very strong heat on her first day to show, urine very cloudy, so semen was ordered immediately for breeding on day 3 & 4 (considering her short cycles). She was infused on day 2, given oxy a few hours later, and HCG. Day 3, the expensive semen arrives, and she was dead out! We attempted to inseminate her (yesterday) and even drugged she was not having it! When in heat, she is no problem. She was not inseminated.

We are in an area where we cannot always get a vet, so must rely more on our experience than technology.

Is there any suggestions or insight you might give so I can figure out what is going on with this mare, and what we might do to get her in foal? She can go back to the farm for live cover. The stallion is very fertile, so it's nothing to do with him.

Thank you.
 

Jos
Board Administrator
Username: Admin

Post Number: 2926
Registered: 10-1999
Posted on Wednesday, June 30, 2010 - 09:08 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

It sounds as though this mare is merely showing the symptoms of a somewhat silent estrus. I suspect too that this last breeding attempt was a situation where a large follicle was present at the time the Prostaglandin F was given, resulting in a rapid onset of estrus and ovulation, which is not unusual (follow those links for more details.

Essentially, she is a mare that needs tighter management with the use of ultrasound rather than relying on teasing. If you cannot arrange that, then you might want to give P&E or biorelease altrenogest a go.
 

Barbara Lewis
Yearling
Username: Baraka

Post Number: 66
Registered: 06-2008
Posted on Wednesday, June 30, 2010 - 09:51 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

Thank you. I will study these articles and seriously consider these methods.

I'm interested in trying the biorelease altrenogest, and have a couple of questions.

How many injections are needed? Can one rely (as well as one can rely on anything to do with horses :-)) on her coming in to heat on a certain day after these injections? Can you please provide me with more detail about how biorelease is used and works?

This biorelease information states that "the veterinarian is the person giving the injections of the compound,.." Is there a reason he should give the injection? If it is IM, is there a reason I cannot do it?

I have heard you speak on P&E in your clinics, but understand that this requires several injections, and is thick. That was a little discouraging for me, so maybe the biorelease will be better.. yes?

Thank you again. You are much appreciated.

Is it common for a mare to show good heat one year, and become a silent mare the next?
 

Jos
Board Administrator
Username: Admin

Post Number: 2929
Registered: 10-1999
Posted on Wednesday, June 30, 2010 - 10:12 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

The biorelease formulation reduces the number of injections required to 3:
  • The biorelease formulation;
  • Prostaglandin F on day 10 (this may be reduced in volume and given on two consecutive days using an insulin syringe which can be less stressful for all concerned. If so, give 1/10th of the full dose on days 9 and 10);
  • The ovulation promoter (hCG, Deslorelin etc)
The biorelease formulation is thick, but possibly not as thick as the P&E. In any case, it's only one shot, so worth any struggle. Onset of estrus will be approximately 14 days after the initial injection in over 80% of instances. Not foolproof, but nothing is in breeding...

Mares, like humans, are individuals and can change their behaviours to some extent...
 

Barbara Lewis
Yearling
Username: Baraka

Post Number: 67
Registered: 06-2008
Posted on Thursday, July 01, 2010 - 07:20 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

Okay, to do the "Repro for Dummies" version and be sure I get this right.

We assume the mare is not in heat... or do an U/S to see where we are.

Provided there is no heat cycle, we give the Biorelease injection.

10 days later, we give Prostaglandin.

Here I am a little confused. You say the Prosta can be reduced and given on two consecutive days (da 9 & 10), then you say we can give 1/10 of the full dose on those days.

Maybe it's obvious, but I'm confused by the dramatic reduction in what she would receive. If a Lutylase "regular" dose is 2 ml, we would just give 1/5 ml, on 2 consecutive days, and that's it? I would have assumed she would get 1 ml each day, so it's great if less will work.

Then, ideally we do an U/S about 14 days after the initial injection, and hCG at the appropriate time.

(I like to think "out loud. )

Thank you.
Barbara
 

Jos
Board Administrator
Username: Admin

Post Number: 2930
Registered: 10-1999
Posted on Thursday, July 01, 2010 - 08:51 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

We assume the mare is not in heat...

Doesn't matter if the mare is in heat or not.

Here I am a little confused. You say the Prosta can be reduced and given on two consecutive days (da 9 & 10), then you say we can give 1/10 of the full dose on those days.

Maybe it's obvious, but I'm confused by the dramatic reduction in what she would receive. If a Lutylase "regular" dose is 2 ml, we would just give 1/5 ml, on 2 consecutive days, and that's it? I would have assumed she would get 1 ml each day, so it's great if less will work.


There is never any need to give a "full" (1-2 ml) dose of Prostaglandin unless one has a bitter and twisted attitude towards one's mares and likes to see them sweat and get crampy! Research released 8 years ago demonstrated that 1/10th of the dose given 2 days consecutively had the same impact on induction of estrus as did a full dose, but with none of the side-effects. In fact, if one is using the synthetic prostaglandin cloprostenol (marketed as Estrumate) one needs only to give 0.1-0.2 ml once. We routinely use only 0.1 ml x 2 days. We also use it as a gauge for evaluating if a veterinarian is "up" on reproductive information. If they are still pumping in the full dose and making those mares sweat, then they're not up to date on reproduction information!!!

Then, ideally we do an U/S about 14 days after the initial injection, and hCG at the appropriate time

Correct. She may only just be entering estrus at that point, but better to do an extra ultrasound than to miss an ovulation...
 

Barbara Lewis
Yearling
Username: Baraka

Post Number: 68
Registered: 06-2008
Posted on Thursday, July 01, 2010 - 09:09 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

Research released 8 years ago demonstrated that 1/10th of the dose given 2 days consecutively had the same impact on induction of estrus as did a full dose, but with none of the side-effects.

GREAT to know. Must admit my ignorance on this one. In my defense, I never gave 2 ml.

Thank you! This information is going to make a huge difference on my farm!

We also use it as a gauge....

It's why I've always put so much stock in your clinics and this forum. Those of us stuck way out in the boonies, can at least do things somewhat right and up to date.

Thank you again,
Barbara



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