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Older maiden; Cushings;Chronic infecton..looking for suggestions

Equine-Reproduction.com Bulletin Board » Breeding Problem Mares - Volume 2 » Older maiden; Cushings;Chronic infecton..looking for suggestions « Previous Next »


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Candace Cotter
Neonate
Username: Candace

Post Number: 1
Registered: 06-2007
Posted on Wednesday, June 20, 2007 - 02:04 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

I have a mare this season that was presented with the following history:

14 yrs old Arabian. Diagnosed (and under treatment for) Cushings and low thyroid. Bred through 3 of 4 previous years with one conception, lost prior to day 35 (two years ago). IA biopsy two years ago. No history of infection, but failure to relax the cervix and fluid retention during estrus.

This season began with the first productive cycle in April, having been under lights through the winter. Mare had good weight, excellent hair coat. Mare is on grass hay, and low carb supplemental feed, also Platinum Performance supplement.

Cultured clean, with a normal cytology prior to first breeding cycle.

Bred through first cycle with first insemination following a 35mm follicle scanned, plus Deslorelin. Oxytocin protocol followed, which included lavage post-breeding in her case. Inseminated twice. Oxytocin used up to three days post breeding. Antibiotic included in last lavage. Elected to use P4LA at 4 days post-ov. (This would appear to have been a bad call in retrospect, as it has immune suppressing effect).

Mare had much fluid and positive culture (Strep and E. coli) at 14 days post-breed. Treated with "Settle" and antibiotic infusion following lavage.
Cultured and biopsied at next cycle...Biopsy IIB and positive for Pseudomonas. Treated with lavage and antibiotics through this last cycle.

Going forward (should this mare culture clean) what would be additional suggestions for proceeding to breed through the cycle. Oxytocin of course, but...? "Pinpoint" breeding if possible, "Settle" at the beginning of the cycle as a precaution? Plasma? Broad spectrum antibiotic following ovulation? We will avoid progesterone supplementation, though may encounter owner resistance.

Any feedback appreciated. I've dealt with a lot of problem mares, but this one has me going, and of course is the owner's best mare. As an additional concern, she has just in the last two weeks begun to grow a longer coat than she previously had.
 

Jan Owen
Breeding Stock
Username: 1frosty1

Post Number: 398
Registered: 04-2006
Posted on Wednesday, June 20, 2007 - 02:09 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

Hi Candace....I am not an expert at all...but my mare had a hard time clearing after being AI'd and on the third try we used settle prior to breeding and then lavage and the Oxytocin protocol and we were successful. So sorry to hear that you are having difficulties. Hope that it works out for you.



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