Can you please elaborate upon this statement made on the "repro" board.........
contemplate putting her on progesterone AND estradiol at 3 days post-ovulation, through to day 18 at least (when you should have her u/s'd). If she's pregnant then, well, maybe keep her on the combination until after days 35 anyway.
What I would like to know is what mare would benefit from this tx? Would this help a mare with post uterine clearance problems given she would have already been lavaged/oxytocin....and then, this treatment? thanks !!
Posted on Tuesday, October 17, 2000 - 06:35 am:
For those who are not members of the EquineRepro e-mail list, I responded there to a question about a mare that appeared to be undergoing repeated early embryonic death with several suggestions, one of which was that the owner may contemplate using the combination of Progesterone and Estradiol post-ovulation rather than using Altrenogest (brand name "Regumate") which is commonly used. My full response can be seen by "clicking" here.
This treatment, which is still not a confirmed positive and/or a recognised treatment, would only be of use in a mare that is apparently loosing early pregnancies as a result of a hormonal inbalance. During early pregnancy Estrogen is important for creating a nutritional uterine environment for the conceptus, and it has been suggested that low endogenous levels can be supplemented by exogenous Estradiol.
It would have no effect on a mare's uterine clearance abilities.
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