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Lutalyse dose too small???

Equine-Reproduction.com Bulletin Board » Hormonal Manipulation » Lutalyse dose too small??? « Previous Next »


Author Message
 

Susan Barta
Weanling
Username: Pniranch

Post Number: 21
Registered: 05-2008
Posted on Wednesday, June 08, 2011 - 07:00 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

I have a mare that ovulated while we were dealing with my father in laws death so this is 8 days post ovulation and the vet left me 2cc's of Lutalyse to short cycle her.

I went to do that tonight and there was only 1cc in the syringe. I saw Jos's posts on micro dosing but I know it would be less than 1cc. Will the 1cc work or do I need to go get another dose tomorrow to give to her and if so how much?

Should I try to micro dose the next two days and if so how much. Jos I would love to know the dosages for this procedure as well as help with this situation and what are the normal dosages.
Thank you, Susan
 

Kristen B.
Weanling
Username: Kristen_b

Post Number: 34
Registered: 06-2010
Posted on Wednesday, June 08, 2011 - 07:06 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

.2 cc's two days in a row :-)
 

Susan Barta
Weanling
Username: Pniranch

Post Number: 22
Registered: 05-2008
Posted on Wednesday, June 08, 2011 - 09:16 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

But what about the fact she had 1cc today. Is that enough or does she need .2 tomorrow??
 

Jos
Board Administrator
Username: Admin

Post Number: 3285
Registered: 10-1999
Posted on Wednesday, June 08, 2011 - 09:49 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

Lutalyse is labelled for use at 1 mg/100 lbs of the active ingredient, so a 1,000 lb horse would receive a full dose of 10 mg. It is packaged at a concentration 5 mg/ml. Consequently, a full dose would equate to 2 ml.

Having said that, and aside from the research published in 2002 which indicates that 1/10th of the full dose (i.e. 0.2 ml) 2 days in a row will have the same effect in causing a return to estrus without any side-effects (and incidentally, at 9 years old, that is pretty old research, and we use it as an indication as to whether the prescribing veterinarian is well-versed and up-to-date in equine reproduction matters - yours would appear not to be), Dr. Pinto when at NCSU found that a single dose of ¼ the full dose would cause a return to estrus as long as all other prerequisites were in place (receptive CL), so based upon that research, you should be fine.
 

Susan Barta
Weanling
Username: Pniranch

Post Number: 23
Registered: 05-2008
Posted on Wednesday, June 08, 2011 - 10:37 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

Thank you Jos,

My vet is not versed in this as you said as he has only been out of Vet school 3 years. He also told me they no longer teach them to palpate in Vet school. I find that not to be a good practice as he has no way but the U/S to go on where a follicle is at and what the tone of the uterus is. If I have any mares I think are in need of more evaluation I haul them to Dennis Smith in Aurora, NE and he is excellent and has been around a long time. We are moving to Colorado this fall so I hope to find a good and experienced reproductive vet there. Thank you again for your timely answer. Considering her CL we should be good to go.
 

Jos
Board Administrator
Username: Admin

Post Number: 3287
Registered: 10-1999
Posted on Wednesday, June 08, 2011 - 11:18 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

Well, FWIW, unless a veterinarian did a special rotation on equine reproduction when going through vet school, the vast majority of them will have done 0-5 palpations (yup - zero to five!) on mares by the time they graduate.

I know quite a few veterinarians personally that had done absolutely no mare palpations prior to going into practice...

Scary when you really think about it - the more so as many vets (especially the newly graduated) will give lay people a lot of grief if they (the lay people) palpate!
 

Susan Barta
Weanling
Username: Pniranch

Post Number: 24
Registered: 05-2008
Posted on Friday, June 10, 2011 - 01:43 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

I so agree with you and yes he had done ZERO when he got out of school. I do have to give him credit for trying though as he is taking every course he can and cooled and frozen semen and learning how to do so and that will take him far. He is a great open minded young vet and I had a breech birth for the first time ever and he got the foal out (dead) in less than two hours and the mare is not damaged (from what the eye can see on U/S and checking her cervix) and is doing well. Some reason I called him as I had a hunch she had a problem even though her water did not break until after he arrived. I am glad I went with my gut on that one!!



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