I have two bottle of compounded P&E due to expire (as per label) in November. Anyway I can keep them until spring? Should I freeze them? Do they truly "expire" or is it more of a "best before"./ Thanks
P&E is not an FDA-tested drug product, consequently nobody has evaluated the viability duration. The date is put on by the compounding pharmacy in a somewhat arbitrary manner (e.g. 3/6/9 months after production etc.). I can say that I have used P&E that has been several years old, and it has behaved in the usual predictable manner, but that will not necessarily be the case with all formulations.
One thing I can say with certainty is do not freeze it! It needs to be kept at approximate room temperature (ideally 40-60° F). If it gets cold (or freezes) the hormones will precipitate out of the carrying agent, and you will have chunks of hormone sitting at the bottom of the liquid. If that happens, you have to resuspend the hormones in the liquid by heating it (so don't let it get cold!!).
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