You will have to read the outside of the bottle that your hCG came in. One cannot convert IU (International Units) to mg (milligrams) as they are two different measurement methods - it would be like trying to convert inches to gallons!
hCG typically comes as a powder - a good example is the product "Chorulon". You will note if you follow that link, that is is packaged as a "freeze-dried preparation of chorionic gonadotropin (human Chorionic Gonadotropin or hCG) for intramuscular administration after reconstitution. When reconstituted with the accompanying sterile diluent, each 10 mL vial contains 10,000 I.U. chorionic gonadotropin" (this is specifically referencing use in bovine or fish. It can also be used IV in the equine). In this instance, the powder is reconstituted with 10 ml of sterile diluent, giving a final concentration of 1,000 IU/ml. (Note that the values do not mention mg!!). In Canada, Chorulon (which is the most commonly used form of hCG in equine reproduction in North America) also comes packaged in 5,000 IU packages of dried powder, making it even more important to check the packaging!
Obviously if the powder is reconstituted at 1,000 IU/ml, then for a 1,500 IU dose, one would use 1½ ml. Do not overdose beyond 3,500 IU in the same cycle as this can actually suppress ovulation - in particular if one reaches the 5,000 IU dosage level (which is important to note in case someone takes the attitude that one can simply "stick the whole vial in the mare"!!).
Once reconstituted, one can draw off suitable volume dosages and freeze those that are not used immediately in the fridge-freezer and air-thaw them later in the same season for use. I would not recommend keeping them beyond one season, but this will save on cost significantly.
Your profile lists you as being located in Alberta, Canada. "Chorulon" (hCG) is available in Canada - one of the links above references Canada - and Estradiol cypionate ("ECP") is also commercially available.
There should be no need to use a compounding pharmacy for either of these products as your veterinarian will be able to purchase them as a ready-made approved product.
hCG is a controlled substance and requires a prescription to obtain. Furthermore it is abused by some people as a "dietary aid" or in body-building practices. It is therefore not protectionism on the part of the veterinarian who will not hand it out, but compliance with legal restrictions! In some cases, a veterinarian with a valid client-patient relationship may release a dose for use, but - again legally speaking - there would have to be a valid client-patient relationship in place, as well as the veterinarian being "comfortable" with releasing the product to the client.
If you are obtaining hCG from a pharmacist without a prescription, that pharmacist is breaking the law. Furthermore, even if you do have a prescription, as there is an approved product available commercially, the pharmacist is breaking the law by compounding an already-available product. The alleged proposed actions of this pharmacist therefore leave me a little leery of the legality of the situation...
No, the pharmacist not once ever mentioned doing this w/o a Rx. In fact always stated a Rx would be required if I could find a vet willing to write a Rx. None of the local vets (not that I have a lot of choices) were willing. I'm rather remote and the closest vet I have is 45 minutes away. Thus, to explain further, the ONLY thing I was wanting was to save on travelling, vet fees and board fees for these 2 mares who should be rather straight-forward to inseminate.
I finally found one vet quite a good distance from my farm, who doesn't do repro work as his maintstay, who is willing to do a pre-breed exam on the 2 mares and then provide me the medications and outline the exact time-table for me, so it all ends well. I am wanting to inseminate the mares myself this year, but it was really hard getting a repro vet to just be willing to do a pre-breed exam and give me the meds for P&E, plus chorulon here and let me have at it. The usual response was "No, not unless I do the mare's insemination as well". In my area, it costs about a $1000 per cycle to have a straight-forward fresh semen AI insemination here (including mare stay), double that for frozen semen.... all I was hoping for was to cut down on vet fees, not insinuating I was wanting to allow something illegal to take place - such does my reputation no good.
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