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Cytology

Equine-Reproduction.com Bulletin Board » Abortion and Pregnancy Loss » Cytology « Previous Next »


Author Message
 

Karen Knight
Weanling
Username: Sparkskaren

Post Number: 31
Registered: 08-2010
Posted on Wednesday, January 25, 2012 - 07:55 am:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

I have a mare that we tried to get in foal last year unsucessfully. On scans before Ovulation she had no Uterine fluid i gave her 3ml of a drug simular to oxytocin 6 hours after AI but a few days after noticed a thick discharge from her. this happend 3 time last year mare not in foal. this year i want to get her checked before we start to breed her when should a Cytology swab/ slide be done? the vet would not do one last year as he said she would have fluid before Ovulation.
 

Jos
Board Administrator
Username: Admin

Post Number: 3466
Registered: 10-1999
Posted on Wednesday, January 25, 2012 - 10:26 am:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

Ideally one performs the swabbing for culture and cytology on the estrus prior to the one you want to breed on, as that gives you that cycle to treat the mare. If there are concerns, performing it on the estrus 2 cycles prior to breeding will give you a little more treatment time if needed.

What was the "drug similar to oxytocin"? Depending upon what it was, dosage and timing can have an impact. Additionally, a single treatment in DUC mares it typically inadequate.

Fluid is not necessarily present in mares with endometritis. Not is there necessarily going to be fluid in the uterus prior to ovulation - in fact it is more likely that there will not be in the majority of mares.
 

Karen Knight
Weanling
Username: Sparkskaren

Post Number: 32
Registered: 08-2010
Posted on Monday, January 30, 2012 - 04:07 am:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

the stuff the vets gave me is called Reprocine 0.07mg/ml and the active ingredient is Carbetocin. do you think i should insist on Oxytocin?

If everything comes back clear what should i be doing with the mare?

I have read your artical on use of Oxytocin but am dyslexic and find it hard to pick out the fact so could i have it in short please, thanks a lot.
 

Jos
Board Administrator
Username: Admin

Post Number: 3472
Registered: 10-1999
Posted on Monday, January 30, 2012 - 09:52 am:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

Carbetocin is a long-acting oxytocin. We do not have access to it in the USA, so I am not familiar with it in entirety, but the half-life is about 40 minutes (as opposed to under 7 minutes with oxytocin) so the repetition rate would be less. I suspect that one should be giving it twice a day instead of four times, but I stand to be corrected on that.

As I am not familiar with carbetocin, I cannot extrapolate the information from the oxytocin protocol for your use. In essence, with oxytocin one uses a low dose (10-20 iu) every 4-6 hours. It is a little more complicated than that, as there are different factors to consider, so perhaps someone reading it for you and explaining the different uses might be better than me getting it wrong for you by not giving all the applicable details. There really is no "short version"! :-) Furthermore, if you are using carbetocin (which is fine) the times and doses will not be the same.
 

Karen Knight
Weanling
Username: Sparkskaren

Post Number: 33
Registered: 08-2010
Posted on Tuesday, January 31, 2012 - 03:12 am:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

Thanks one last question would this mare be better with fresh semen than chilled? as i have read that whole semen has got anti-inflammatory properties? who this help her?

The only foal she has bred so far has been with Fresh semen.
 

Jos
Board Administrator
Username: Admin

Post Number: 3474
Registered: 10-1999
Posted on Tuesday, January 31, 2012 - 10:28 am:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

It's a catch-22 situation. While undiluted seminal plasma has greater anti-inflammatory properties, without extender (with antibiotic in, which it should have) the bacteria that will be present offer a greater inflammatory risk.

We go with extender and good management. :-)
 

Karen Knight
Weanling
Username: Sparkskaren

Post Number: 34
Registered: 08-2010
Posted on Wednesday, February 01, 2012 - 03:23 am:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

OK thanks



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