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Attn JOS

Equine-Reproduction.com Bulletin Board » Breeding Problem Mares - Volume 1 » Attn JOS « Previous Next »


Author Message
 

Lindros
Nursing Foal
Username: Lindros

Post Number: 17
Registered: 02-2006
Posted on Tuesday, May 30, 2006 - 07:22 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

Please be so kind and give me your opinion on the following situation.
One of our mares returned from KY a few days ago. She's just over 60 days in foal. She is on 10 cc Regumate and has also been getting an injection of P + E once a week. The reason she has been getting the P + E is because her progesterone level is extremly low. It was < 1 when they tested her, a few days ago it was 2.
Any thoughts?
 

Jos
Board Administrator
Username: Jos

Post Number: 10703
Registered: 10-1999
Posted on Tuesday, May 30, 2006 - 10:30 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

I think the article on this site entitled "does my mare need Regumate?" will go a long way to answering many of your questions.

Unless BET Pharm BioRelease P+ LA is being used, there is probably little value in use of P&E as it is designed to be completely absorbed by the body within about 24 hours - that's why one has to give it daily for 10 days.

Remember too that a single blood progesterone assay is not necessarily going to be reliable for an indication of inadequate (or adequate) progesterone levels, as the levels will vary - in some cases dramatically - during the day and/or from day to day. A series of 3 or 4 tests for 3 or 4 days in a row is necessary to gain accurate insight.

If the use of progestin supplementation in your mare makes you sleep easier though, then that is worth something!
 

Lindros
Nursing Foal
Username: Lindros

Post Number: 18
Registered: 02-2006
Posted on Wednesday, May 31, 2006 - 06:34 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

Jos, thank you for your answer!
The mare has a history of early pregnancy loss, that's why she's on regumate. I am aware of the fact that regumate tends to get used more often than truly necessary. That wasn't really what I was asking about.
I am just wondering why one would put a pregnant mare on P + E in the first place? Versus just progesterone.
Thank you for your time!
 

Jos
Board Administrator
Username: Jos

Post Number: 10719
Registered: 10-1999
Posted on Thursday, June 01, 2006 - 03:24 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

It may be that the person prescribing it thinks that it would be beneficial. The addition of the estrogen may be beneficial, but as I note above, P&E is absorbed at a daily rate, so using it three times a week would have questionable elevation abilities.



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