Please be so kind and give me your opinion on the following situation. One of our mares returned from KY a few days ago. She's just over 60 days in foal. She is on 10 cc Regumate and has also been getting an injection of P + E once a week. The reason she has been getting the P + E is because her progesterone level is extremly low. It was < 1 when they tested her, a few days ago it was 2. Any thoughts?
Unless BET Pharm BioRelease P+ LA is being used, there is probably little value in use of P&E as it is designed to be completely absorbed by the body within about 24 hours - that's why one has to give it daily for 10 days.
Remember too that a single blood progesterone assay is not necessarily going to be reliable for an indication of inadequate (or adequate) progesterone levels, as the levels will vary - in some cases dramatically - during the day and/or from day to day. A series of 3 or 4 tests for 3 or 4 days in a row is necessary to gain accurate insight.
If the use of progestin supplementation in your mare makes you sleep easier though, then that is worth something!
Jos, thank you for your answer! The mare has a history of early pregnancy loss, that's why she's on regumate. I am aware of the fact that regumate tends to get used more often than truly necessary. That wasn't really what I was asking about. I am just wondering why one would put a pregnant mare on P + E in the first place? Versus just progesterone. Thank you for your time!
It may be that the person prescribing it thinks that it would be beneficial. The addition of the estrogen may be beneficial, but as I note above, P&E is absorbed at a daily rate, so using it three times a week would have questionable elevation abilities.
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