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MicroLactin reduce Neutrophil response?

Equine-Reproduction.com Bulletin Board » Breeding Problem Mares - Volume 1 » MicroLactin reduce Neutrophil response? « Previous Next »


Author Message
 

Sharon Malmberg
Nursing Foal
Username: Ryu2832

Post Number: 11
Registered: 02-2006
Posted on Wednesday, March 08, 2006 - 09:08 am:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

I was wondering if MicroLactin could help reduce the neutrophil response in the uterus after AI.

It is used widely as a supportive supplement to NSAIDs in dogs to reduce the neutrophil response due to chronic inflammation.

What I've read says it's not tissue specific. Just a thought...
 

Jos
Board Administrator
Username: Jos

Post Number: 10509
Registered: 10-1999
Posted on Wednesday, March 08, 2006 - 10:28 am:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

It might, although I am not aware of it's being used in the equine - primarily because you want that post-breeding inflammatory response, and without it the mare will typically become infected as a result of pathogenic presence introduced during the breeding procedure and estrus while the cervix is relaxed!

Use of ecbolics post-breeding to assist in delayed uterine clearance if it an issue is the normal mode of treatment of post-breeding uterine issues.
 

Sharon Malmberg
Nursing Foal
Username: Ryu2832

Post Number: 13
Registered: 02-2006
Posted on Wednesday, March 08, 2006 - 11:17 am:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

Well I was just thinking. If she's going to get a lavage with antibiotics anyway...

She mounts a mighty inflammatory response after AI. I have my suspicions that the inflammatory response isn't tapering off as it should. I am concerned that she is being put on Regumate before the response is tapered off, and that is the fluid that isn't clearing.

I was just thinking that maybe I could time it with the breeding, give a course of MicroLactin before the breeding. Or in her case a better plan might be to time it for 2-3 days after breeding to help stop the inflammation response once it's done it's job.

Oh well, I'm sure my vet will give me the 'nutty owner' look and go on with her business. I'm a molecular geneticist by trade, what do they say--a little knowledge is dangerous?? Danger, danger!

Thanks for letting me bounce an idea off of you!



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