When breeding a mare with delayed clearance, what "other" drugs are deemed appropriate....especially when the days post breeding are over 2 and under 6 and there is still some minimal fluid noted? Also, if the mare is a candidate for Regumate supplementation, when should this be started based upon delayed uterine clearance syndrome. Thanks Jos!
Jos
Posted on Thursday, August 17, 2000 - 11:53 am:
The conceptus does not descend into the uterus for a minimum of four and-a-half days post ovulation, and more usually it is closer to 6 days. You are safe therefore to use a drug such as Oxytocin for 4 days post-ovulation in order to assist in fluid removal. Obviously, after that point, there is a danger of removing the conceptus, and further treatment is therefore not recommended!
Note that the important time-line is ovulation, rather than breeding.
The use of Regumate, or any other Progestogen product may be contra-indicated if the fluid retension is persistent, as these hormones may encourage the retension. Care should therefore be taken when using them. You maybe facing somewhat of a "catch 22" situation if you have a mare who is inclined to lose pregnancies due to EED, in that ideally you will want to start the Regumate at 3 to 5 days post-ovulation. This can therefore be in conflict with the fluid problem. This late in the year, I think maybe I would feel inclined to be agressive with your Oxytocin treatment (4x daily for 3 days post-ovulation) and start the Regumate on day 4 (or day 3 if ultrasound reveals no uterine fluid).
Good luck!
Karen in Maine Posted From: 66.186.178.33
Posted on Sunday, June 29, 2003 - 07:58 am:
What is this delayed Clearance?? I see it on here alot and have no idea what it means.
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