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Mare not responding to Lutalyse

Equine-Reproduction.com Bulletin Board » Breeding Problem Mares - Volume 1 » Mare not responding to Lutalyse « Previous Next »


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Sandy
Posted From: 67.31.169.45
Posted on Saturday, June 07, 2003 - 07:51 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

Mare is 8 years old, is 30 days post foaling, has not had a heat cycle since foaling, (have been teasing her with stud since day 5 post foaling), administered Lutalyse injection 7 days ago, and she is still not showing one single sign of being in heat.
This same mare 3 years ago did the same thing, showed absolutely no heat after foaling, I waited until the foal was weaned (3 months later) and gave her a Lutalyse shot and she came into heat on day 4 and was bred successfully and settled.

So, what is the difference this year? Is it because the foal is still nursing? Am I going to have to wait another 2 months, wean the foal and try again? That will put me breeding her in August, which I really didn't want to do. When the vet palpated, he said that she was just "inactive". Do you think that if I just wait another month and try the shot again that it might work? I'm just really frustrated with this mare. Any suggestions or comments from anyone that has experienced this before would be greatly appreciated.
 

Jos
Posted From: 158.252.241.166
Posted on Saturday, June 07, 2003 - 10:24 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

Prostaglandin F2a (Lutalyse) will not induce estrus in a mare that does not have a functional CL present, so she must have had a previous ovulatory cycle. Additionally the time the PGF2a is given is critical.

Some post-foaling mares become anestrus when nursing the foal - in other words they do not have heat cycles and/or ovulate. Other mares will not display estrus even though they are actually cycling. There is more information available on this subject on this site here.

A blood-progesterone assay is valuable in these mares, as if progesterone is present, that indicates the mare is in fact cycling. If that is the case, she will respond to prostaglandin, or - more effectively - "P&E". With the use of this latter hormone combination, one can pinpoint the ovulation, which makes life much easier with "silent" mares.
 

Sandy
Posted From: 67.31.172.42
Posted on Saturday, June 21, 2003 - 02:17 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

Update on mare:
This mare finally came into heat 14 days after giving the Lutalyse. Which in actuality turned out to be a 30 day post foaling heat cycle.
She accepted the stallion for 5 days and then went out of heat. We're now waiting so we can have her checked to see if she settled.



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