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Help with biopsy and treatment

Equine-Reproduction.com Bulletin Board » Breeding Problem Mares - Volume 1 » Help with biopsy and treatment « Previous Next »


Author Message
 

Robin Muse (205.188.199.154)
Posted on Monday, June 11, 2001 - 10:15 am:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

Biopsy report came back as insufficient for assigning a Kenny grade. Before spending more money to redo, does this look like a 111?

The epithelium is composed of medium to tall columnar cells. Occasional scattered lymphocytes are noted throughout the stratum compactum and stratum spongiosum. There is moderate glandular density. Endometrial glands are lined by medium to high epitheal cells. Glands are linear and multifocally contain moderate amounts of eosinophilic material. A single glandular nest is cuffed by six layers of fibroblasts. there is a single eosinophil in this fibrosis. Special staining for elastic fibers demonstate mild deposition.

History of mare:
12 yr old. breed 1st time 1996-had colic surgery at 9 mos. lost foal a month later. tearing etc. with dead foal delivery.

bred again 1998- foal 1999 fine

bred 2000- frozen semen preg. 1st insemination -checked in at 14 days gone by day 35

bred twice this year - 1st breeding didn't ovulate on first insemination, 2nd delvery of semen lost in shipping.

bred again with timing perfect-no embryo

Mare was cultured neg. prior to 1st breeding.
Recultured with cytology (neg) and biopsy report above.

Vet wants to do DMSO lavages. I would like to know more about them.Is the purpose to irritate the uterus or take out inflamation? I would like to be able to use this mare again as a broodmare if possible, but if she can't I don't want to keeps messing with her. Oxytocin was used 1 dose 4 hrs after all breedings. Small amount of fluid was found only after the second breeding. She was ultrasounded 48 hrs after breeding.

Any ideas? Rebreed? Reculture? Let her rest? DMSO? Thanks for any input.



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