Has anyone had experience with the deep uterine insemination technique using frozen semen? I have been able to obtain some studies and articles which explain the technique, but I would like to hear from those who've had personal experience with this technique. Answers to the following questions would be helpful: --How many doses or partial doses were used per insemination? --How many million sperm were used per insemination? --How many inseminations per cycle, i.e. pre, post or pre and post-ovulation? --Were any hormones administered during the cycle? --What was the first cycle conception rate? --Second cycle conception rate? --Did there seem to be an inflammatory response of the uterus to a greater degree than what might normally be expected post-insemination? --Did the technique cost the same as or more than traditional insemination protocols? --Do you think this is an efficient, cost-effective insemination technique? --Any other insights or suggestions? Thank you in advance for any assistance. Carol Austin
Posted on Wednesday, January 01, 2003 - 11:19 pm:
At the ISER this past summer there was a presentation made - I believe by Squires et. al. (CSU) - which discussed deep uterine insemination (DUI) techniques, and which essentially said that if one was using a standard insemination dose of sperm (i.e +/- 200 million progressively motile) then the use of DUI actually resulted in lower conception rates when compared to regular uterine body inseminations. In the event however that sub-optimal sperm doses were being used (varying in numbers down to 1 million, with corresponding pregnancy rate reduction), then higher pregnancy rates were achieved than with standard uterine body inseminations.
In light of my above comments, I suspect that the majority of your question was answered, as I think you were looking at the use of DUI in connection with standard frozen semen insemination techniques (doses). If you do have more questions, and would like to rephrase them to be more specific, I will be happy to attempt to assist.
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