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Mongoloid in foals?

Equine-Reproduction.com Bulletin Board » Equine Genetics » Mongoloid in foals? « Previous Next »


Author Message
 

Mary Susan Newill
Neonate
Username: Msnewill

Post Number: 8
Registered: 06-2005
Posted on Sunday, January 29, 2006 - 11:30 am:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

Was just wondering if this is a possibility in horses as it is in humans-chromosome messup?
Anyone heard of or seen anything>
Susan
 

Jenn
Yearling
Username: Jenn

Post Number: 72
Registered: 01-2006
Posted on Sunday, January 29, 2006 - 02:26 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

I have heard of foals having mental problems from birthing issues (usually lack of oxygen) but not chromosome problems like in humans.
 

Heather Kutyba
Weanling
Username: Heatherck11

Post Number: 36
Registered: 01-2006
Posted on Sunday, January 29, 2006 - 03:15 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

Barring normal circumstances, I'd never say never.
Not pertaining to horses, but for good example...
I manage a small animal hospital, and we have a cat that we've seen since he was 5 weeks old that has a form of "Downs Syndrome"....baffled all the specialists...said it couldn't happen, then had to eat their words.
Like the human afflicted, this kitty is the SWEETEST critter I've ever been around, but it's condition is remarkable.
 

Deena
Breeding Stock
Username: Morganslil1

Post Number: 220
Registered: 04-2005
Posted on Sunday, January 29, 2006 - 04:15 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

Horses do have genetic defects and yes there is a defect that resembles Trisome 21 or downs syndrome although I believe it is quiet rare.
Deena
 

Mary Susan Newill
Neonate
Username: Msnewill

Post Number: 9
Registered: 06-2005
Posted on Sunday, January 29, 2006 - 08:14 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

Deena, do you know what it looks like ?
susan
 

Deena
Breeding Stock
Username: Morganslil1

Post Number: 221
Registered: 04-2005
Posted on Sunday, January 29, 2006 - 09:07 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

Heres a brief description small for their age,abnormal gait,and poor comformation. its more likely to occur in older mares.Hope this helps.Deena
 

Jennifer Demski
Weanling
Username: Jennifer_d

Post Number: 25
Registered: 11-2005
Posted on Tuesday, January 31, 2006 - 05:01 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

Deena,

Do you mean older mares are more likely to have a foal with this defect? Interesting.
 

Jenn
Yearling
Username: Jenn

Post Number: 76
Registered: 01-2006
Posted on Tuesday, January 31, 2006 - 05:32 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

The risks also increase with the age of the mother in humans as well.
 

Deena
Breeding Stock
Username: Morganslil1

Post Number: 222
Registered: 04-2005
Posted on Tuesday, January 31, 2006 - 09:34 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

Yeah jennifer but I would imagine that there are exceptions.I know there are exceptions in humans because I happen to have a daughter with downs syndrome(trisomey 21) and I was only 17 when I had her.
 

Jos
Board Administrator
Username: Jos

Post Number: 10434
Registered: 10-1999
Posted on Tuesday, January 31, 2006 - 10:38 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

If you can round up the research paper that confirms the presence of this condition in the equine, I would be interested to have the citation as I am not aware of any such research confirming it.

Thanks! :-)
 

Deena
Breeding Stock
Username: Morganslil1

Post Number: 223
Registered: 04-2005
Posted on Wednesday, February 01, 2006 - 06:19 am:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

The only thing Ive read Jos is about 6 cases in my UC davis book
 

Deena
Breeding Stock
Username: Morganslil1

Post Number: 224
Registered: 04-2005
Posted on Wednesday, February 01, 2006 - 06:43 am:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

Autosomal Abnormalities An extra autosomal chromosome has been identifiedin each of 4 cases of yearlings,described as being small for their age,with abnormal gait and poor comformation.At least two of these cases were foals produced by older mares- a condition reminiscent of human autosomal trisomy (down's Syndrome)whose incidence is highly correlated with increased maternal age.Jos I try to be as accurate as possible.I just wish I knew a 1/10 of what you do.If you do find any case studies would you care to share?Still living and learning.Deena
Heres a link.
http://www.uky.edu/Ag/VetScience/q/2001/jan01/q_main.htm

(Message edited by morganslil1 on February 01, 2006)
 

Jos
Board Administrator
Username: Jos

Post Number: 10437
Registered: 10-1999
Posted on Wednesday, February 01, 2006 - 02:35 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

Thank you for the link.

The chromosomal abnormality on the sex chromosome I am familiar with having seen several mares with the condition. It is generally considered analagous to Turner's syndrome in humans [hmm.. just re-read the article and see that it says that there!!!]. The other situations I am not familiar with, and it appears are considerably rarer.

Don't be concerned about that fact you're still learning - we all are! The day we stop is the day we die (or are finally recognised as being very stupid)! The older I get, the less I know!!! :-)

(Message edited by Jos on February 01, 2006)
 

Deena
Breeding Stock
Username: Morganslil1

Post Number: 225
Registered: 04-2005
Posted on Wednesday, February 01, 2006 - 04:38 pm:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

Jos dont change. I for one enjoy your wisdom after all we all need people we can look up to and respect .You just seem to be one of a very few that cause me to put my hat in my hand.
 

Lisa Weir
Breeding Stock
Username: Pals_pal

Post Number: 133
Registered: 08-2005
Posted on Thursday, February 02, 2006 - 06:17 am:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

Just a question....Are these horses short but heavy, with very large heads and joints? And is the gait more like scrabbling than cantering, etc?

Ok...that's two questions. Sorry! I ask because we had a very strange foal born a few years ago.
 

Deena
Breeding Stock
Username: Morganslil1

Post Number: 226
Registered: 04-2005
Posted on Thursday, February 02, 2006 - 06:27 am:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

lisa im not sure They are quiet rare follow the link above and read it.mabe it will help Deena
 

Lisa Weir
Breeding Stock
Username: Pals_pal

Post Number: 134
Registered: 08-2005
Posted on Friday, February 03, 2006 - 09:24 am:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

Must not have been. He's still alive as far as I know.

This foal looked kind of like he was a dwarf. He wasn't so bad as a wee one, normal size for a first foal, but a little heavy. But as he grew, he just got horse width legs but pony length, a horse body and head. And he walked and trotted funny, and his canter was almost hilarious. He matured to abuout 14 h and his parents were both around 16.3h.

We gelded him young to keep his growth plates open a little longer, but it didn't seem to help. And we had a few vets look at him. They laughed at first sight and then were baffled by him.

I believe he is now a bush hack for someone who loves him to death and doesn't mind his odd action. He was a sweet natured thing.
We called him Thomas...after the tank engine. lol
 

Kim Winter
Breeding Stock
Username: Clafairy

Post Number: 123
Registered: 07-2005
Posted on Friday, February 03, 2006 - 09:44 am:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

Funny.... I have never really thought about this but what you described above is not unlike a pony I know - He was a coloured cob, Should have matured to aroung 15hh but has only made about 13.2hh He is rather out of proportion but he's confirmation is fine. He has a hilarious canter too and when he was months old he was extremely unco-ordinated even in walk. He would lean on you and turn his head sideways as though he couldnt use one eye and stumble alot. Now at Just under three years they are breaking this pony he still has this really thick coat that causes him to sweat buckets throughout the summer and he still suffers from some stifle problem where his leg locks. Its disgusting but the man who owns him is a farmer and he will only treat him as he does the cows, he wont put in the money that you should be prepared to spend on a horse in order for a vet to see him! I no longer see this horse but I know that the symptoms are on going...ANy ideas on that..?
 

Lisa Weir
Breeding Stock
Username: Pals_pal

Post Number: 136
Registered: 08-2005
Posted on Sunday, February 19, 2006 - 10:50 am:   Edit Post Delete Post    Move Post (Moderator/Admin Only)

I'm not too sure. Thomas moved away from us as a yearling and we get very few updates on his progress. I wouldn't say he was uncoordinated as such, there was no wobbling or swaying. He just kind of scrabbled I guess. And he shed normally up until he left so I assume he still does.

The pony sounds like he may have some kind of metabolic disorder?



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